Provided by David Satcher, M.D., Ph.D.
Surgeon General of the United States of America
Chapter 2
Overview of Prevention
Risk Factors and Protective Factors
The concepts of risk and protective factors, risk reduction,
and enhancement of protective factors (also sometimes referred to as fostering
resilience) are central to most empirically based prevention programs. Risk
factors are those characteristics, variables, or hazards that, if present for a
given individual, make it more likely that this individual, rather than someone
selected at random from the general population, will develop a disorder (Garmezy,
1983; Werner & Smith, 1992; IOM, 1994a). To qualify as a risk factor the
variable must antedate the onset of the disorder. Yet risk factors are not
static. They can change in relation to a developmental phase or a new stressor
in one’s life, and they can reside within the individual, family, community, or
institutions. Some risks such as gender and family history are fixed; that is,
they are not malleable to change. Other risk factors such as lack of social
support, inability to read, and exposure to bullying can be altered by strategic
and potent interventions (Coie & Krehbiel, 1984; Silverman, 1988; Olweus, 1991;
Kellam & Rebok, 1992). Current research is focusing on the interplay between
biological risk factors and psychosocial risk factors and how they can be
modified. As explained earlier, even with a highly heritable condition such as
schizophrenia, concordance studies show that in over half of identical twins,
the second twin does not have schizophrenia. This suggests the possibility of
modifying the environment to eventually prevent the biological risk factor
(i.e., the unidentified genes that contribute to schizophrenia) from being
expressed.
Prevention not only focuses on the risks associated with a particular illness or
problem but also on protective factors. Protective factors improve a person’s
response to some environmental hazard resulting in an adaptive outcome (Rutter,
1979). Such factors, which can reside with the individual or within the family
or community, do not necessarily foster normal development in the absence of
risk factors, but they may make an appreciable difference on the influence
exerted by risk factors (IOM, 1994a). There is much to be learned in the mental
health field about the role of protective factors across the life span and
within families as well as individuals. The potential for altering these factors
in intervention studies is enormous. The construct of “resilience” is related to
the concept of protective factors, but it focuses more on the ability of a
single individual to withstand chronic stress or recover from traumatic life
events. There are many different perceptions of what constitutes resilience or
“competence,” another related term. Despite the increasing popularity of these
ideas,“virtually no intervention studies have been conducted that test the
outcomes of resilience variables” (Grover, 1998).
Preventive researchers use risk status to identify populations for intervention,
and then they target risk factors that are thought to be causal and malleable
and target protective factors that are to be enhanced. If the interventions are
successful, the amount of risk decreases, protective factors increase, and the
likelihood of onset of the potential problem also decreases. The risks for onset
of a disorder are likely to be somewhat different from the risks involved in
relapse of a previously diagnosed condition. This is an important distinction
because at-risk terminology is used throughout the mental health intervention
spectrum. The optimal treatment protocol for an individual with a serious mental
condition aims to reduce the length of time the disorder exists, halt a
progression of severity, and halt the recurrence of the original disorder, or if
not possible, to increase the length of time between episodes (IOM, 1994a). To
do this requires an assessment of the individual’s specific risks for
recurrence.
Many mental health problems, especially in childhood, share some of the same
risk factors for initial onset, so targeting those factors can result in
positive outcomes in multiple areas. Risk factors that are common to many
disorders include individual factors such as neurophysiological deficits,
difficult temperament, chronic physical illness, and below-average intelligence;
family factors such as severe marital discord, social disadvantage, overcrowding
or large family size, paternal criminality, maternal mental disorder, and
admission into foster care; and community factors such as living in an area with
a high rate of disorganization and inadequate schools (IOM, 1994a). Also, some
individual risk factors can lead to a state of vulnerability in which other risk
factors may have more effect. For example, low birthweight is a general risk
factor for multiple physical and mental outcomes; however, when it is combined
with a high-risk social environment, it more consistently has poorer outcomes (McGauhey
et al., 1991). The accumulation of risk factors usually increases the likelihood
of onset of disorder, but the presence of protective factors can attenuate this
to varying degrees.
The concept of accumulation of risks in pathways that accentuate other risks has
led prevention researchers to the concept of “breaking the chain at its weakest
links” (Robins, 1970; IOM, 1994a). In other words, some of the risks, even
though they contribute significantly to onset, may be less malleable than others
to intervention. The preventive strategy is to change the risks that are most
easily and quickly amenable to intervention. For example, it may be easier to
prevent a child from being disruptive and isolated from peers by altering his or
her classroom environment and increasing academic achievement than it is to
change the home environment where there is severe marital discord and substance
abuse.
Because mental health is so intrinsically related to all other aspects of
health, it is imperative when providing preventive interventions to consider the
interactions of risk and protective factors, etiological links across domains,
and multiple outcomes. For example, chronic illness, unemployment, substance
abuse, and being the victim of violence can be risk factors or mediating
variables for the onset of mental health problems (Kaplan et al., 1987). Yet
some of the same factors also can be related to the consequences of mental
health problems (e.g., depression may lead to substance abuse, which in turn may
lead to lung or liver cancer).
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